| != | Not Equal to | |
| #! | Shebang | |
| ### | Doublespace Compressed Volume File | |
| #SC | South Central | |
| /. | Slashdot | |
| 0TW | Zero Time Winner | |
| 100B-FX | 100BASE-FX | |
| 100B-T | 100BASE-T | |
| 100B-TX | 100BASE-TX | |
| 100BVG | 100BASE-VG | |
| 10B-F | 10BASE-F | |
| 10B-FB | 10BASE-FB | |
| 10B-FL | 10BASE-FL | |
| 10B-FP | 10BASE-FP | |
| 10B-T | 10BASE-T | |
| 10B2 | 10BASE-2 | |
| 10B5 | 10BASE-5 | |
| 1NF | First Normal Form | |
| 2.5D | Two-And-A-Half-Dimensional | |
| 286 | Intel 80286 processor | |
| 2B1Q | 2 Binary 1 Quaternary | |
| 2FA | Two-factor authentication | |
| 2GL | Second-Generation Programming Language | |
| 2KB | 2,000 Bytes | |
| 2NF | Second Normal Form |
| 386 | Intel 80386 processor | |
| 3DCG | Three-Dimensional Computer Graphics | |
| 3DS | 3 Dual Screen | |
| 3DS | Nintendo 3DS | |
| 3GL | Third-Generation Programming Language | |
| 3GPP | 3rd Generation Partnership Project—’3G comms | |
| 3GPP2 | 3rd Generation Partnership Project 2 | |
| 3LS | 3rd Level Support | |
| 3NF | Third Normal Form | |
| 3PV | Peak Player Production Values | |
| 486 | Intel 80486 processor | |
| 4B5BLF | 4 Byte 5 Byte Local Fiber | |
| 4G | Fourth Generation | |
| 4GL | Fourth-Generation Programming Language | |
| 4NF | Fourth Normal Form | |
| 5GL | Fifth-Generation Programming Language | |
| 5NF | Fifth Normal Form | |
| 6NF | Sixth Normal Form | |
| 802.11 | Wireless LAN | |
| 8B10BLF | 8 Byte 10 Byte Local Fiber | |
| == | Equal to | |
| A-OLS | Administrators Online | |
| A11Y | Accessibility | |
| A2HS | Add to Home Screen | |
| AAA | Authentication Authorization, Accounting |
| AABB | Axis Aligned Bounding Box | |
| AAC | Advanced Audio Coding | |
| AAC-LD | Advanced Audio Coding – Low Delay | |
| AACE | Association for Advancement of Computing in Education | |
| AACE | Association of the Advicement of Computing in Education | |
| AACP | Association of Ahmadi Computer Professionals | |
| AACS | Attendance Allowance Computer System | |
| AAFC | Advanced Air Fuel Computer | |
| AAFS | Activate Arabic Form Shaping | |
| AAL | ATM Adaptation Layer | |
| AALC | ATM Adaptation Layer Connection | |
| AAO | Alt Approving Official | |
| AARP | AppleTalk Address Resolution Protocol | |
| ABAC | Attribute-Based Access Control | |
| ABAC | Association of Business and Administrative Computing | |
| ABACUS | Atari Bay Area Computer Users Society | |
| ABACUS | Architecture and Building Aids Computer Unit Suggest | |
| ABCL | Actor-Based Concurrent Language | |
| ABCS | Advanced Biomedical Computational Science | |
| ABCSA | Akhil Bhartiya Computer Siksha Abhiyan | |
| ABCSA | Akhil Bhartiya Computer Shiksha Abhiyan | |
| ABI | Application Binary Interface | |
| ABL | Adblock Latitude | |
| ABM | Asynchronous Balanced Mode | |
| ABR | Area Border Router |
